Our Research Grounded in Science, Empowered by Collaborative Partnerships

At Hydrosome Labs, our commitment to advancing ultrafine bubble technology is rooted in a robust, science-first approach. Our dedicated team, comprised of PhD and Master’s level scientists, spearheads our research and development efforts. To date, we’ve embarked on over 100 scientific studies, forging partnerships with leading academic and clinical research institutions such as the University of Chicago, University of Illinois, Berkeley Labs, Cornell, NC State, TRI Princeton, SGS, and KGK, to explore the vast potential of ultrafine bubbles.

These collaborative efforts have yielded more than 120 studies, each contributing to our deepening understanding of ultrafine bubble science. Our research encompasses a wide range of applications, from enhancing water quality to improving agricultural yields and beyond. By working alongside esteemed universities and clinical research laboratories, we are not just exploring the boundaries of what ultrafine bubbles can do; we are setting new standards for innovation and efficacy in the field.

Interested in Reviewing our White Papers and Publications?

Enhancing Aerobic Fermentation Efficiency with Hydrosome Lab's Ultrafine Bubble Technology

A University of Illinois Pilot Study White Paper

The Influence of Ultrafine Bubbles on the Metabolic Processes of Escherichia coli

RNA Sequencing of Cells Exposed to Ultrafine Bubbles

Enhancing Niacinamide Delivery into Human Skin with Hydrosome H2O

A TRI Princeton Ex-vivo Study White Paper

Effects of Ultrafine Bubbles on Emulsions and Texture

Improvements in Stability and Consistency

Effects of Ultrafine Bubble Water on Gut Microbiota Composition and Health Markers in Rats

Paper Published in Nanomaterials | 5 August 2025

Dose-Dependent Enhancement of Peak Respiration Rate and Glucose Metabolism in Yeast with Ultrafine Bubble Technology

A Biocell Energetics study at the University of Birmingham (UK)

Increased Biomass Yield of Filamentous Fungi

In this proof of concept study with a fermentation partner, the objective was to understand the impact that Hydrosome H2O could have on the growth of filamentous fungi.

S. cerevisiae: Faster Growth & Higher Biomass

This in house study was designed to demonstrate the impact that Hydrosome Labs technology has on the growth of yeast, using a continuous supply of ultrafine bubbles.

Improved Yields in Precision Fermentation

In this bench scale study with a fermentation partner, the objective was to understand the impact that Hydrosome H2O could have on the yield of a target compound from a precision fermentation

Fermentation: Faster with Higher Yields

This study, done at the University of Illinois Integrated Bioprocessing and Research Laboratory (IBRL), was to demonstrate the impact of Hydrosome Labs technology on cell growth and biomass in a pilot scale fed batch fermentation.

Food and Beverage Applications of Ultrafine Bubbles

The applications of Hydrosome Labs ultrafine bubble technology to the food and beverage industry.

Improved Sytenol (Retinol) Delivery and Stability

In this study, Hydrosome Labs contracted with TRI Princeton to investigate improved skin delivery and stability of sytenol (also known as bakuchiol, a retinol alternative) when formulated with Hydrosome H2O.

Improved Hydration in Skincare Formulations

In this study, Hydrosome Labs collaborated with TRI Princeton, a well respected cosmetics research lab, to understand the effects of Hydrosome H2O on the hydration of human skin samples.

Improved Carnosine Delivery

In this study, Hydrosome Labs contracted with TRI Princeton to investigate improved skin permeation of carnosine when formulated with Hydrosome H2O. Carnosine is a common skincare active ingredient used for its anti-oxidant and anti-aging effects.

Improved Zinc Uptake

In this study, Hydrosome Labs partnered with a third party laboratory to show the cellular uptake of zinc in deionized water as compared to Hydrosome H2O. Zinc is heralded for its health benefits and the ability of Hydrosome H2O to effectively deliver this nutrient could lead to better outcomes for consumers.

Enhanced Fermentation Yields

In this study, Hydrosome Labs partnered with a leading precision fermentation company to observe the growth differences in Pichia Pastoris in the presence of Hydrosome H2O. The ability of Hydrosome H2O to enhance microbial fermentation yields can make it a valuable technology for a multitude of industries.

Enhanced Cannabis Yields with 50% Fertilizer Reduction

In this study, Hydrosome Labs partnered with a licensed cannabis grower to determine if Hydrosome H2O can increase cannabinoid and terpene levels when combined with timed fertilizer adjustments.

Sanitation Enhancement with Hydrosome H2O

In this study, Hydrosome Labs partnered with a leading probiotics manufacturer to evaluate the antimicrobial effects of Hydrosome H2O on various bacterial strains grown in a ginseng (antimicrobial) media.

Improved Cannabis Root Mass

Hydrosome H2O can increase root mass during cannabis cutting propagation.

Improved Niacinamide Delivery

In this study, Hydrosome Labs contracted with TRI Princeton to investigate improved delivery of niacinamide when formulated with Hydrosome H2O. Niacinamide is a common skincare active ingredient used to improve skin resiliency and texture.

Improved Delivery and Stability in Vitamin C Formulation

In this study, Hydrosome Labs contracted with TRI Princeton to investigate improved delivery of Everwhite (Vitamin C) when formulated with Hydrosome H2O.

Dandelion Study for Rubber Production

This study conducted by Hydrosome Labs, compares the growth rate and health of Hydroponic Dandelion Root (an alternative source of rubber) grown in Spring Water vs. Hydrosome H2O.

Improved Niacinamide Penetration

Hydrosome Labs contracted with TRI Princeton to show improved skin penetration