RESEARCH

Improved Niacinamide Penetration

Improved Niacinamide Penetration

Objective

Hydrosome Labs contracted with TRI Princeton to show improved skin penetration of  Niacinamide in a formulation of Niacinamide + Ultra Pure Water as compared to Niacinamide + Hydrosome H2O.

Design

Niacinamide is a common skincare active ingredient used to improve skin resiliency and texture. In this study, Niacinamide was added to both Ultra Pure Water and Hydrosome H2O. The two were then introduced to human skin tissue in a Franz Cell system and were allowed to penetrate for 2 hours.  Confocal Raman Spectroscopy was used to measure the depth of penetration of the Niacinamide.

Results

The results of this study showed that  Niacinamide +  Hydrosome H2O penetrated 2-3X deeper into the skin samples vs Niacinamide + Ultra Pure Water.

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