RESEARCH

Improved Yields in Precision Fermentation

Improved Yields in Precision Fermentation

Objective

In this bench scale study with a fermentation partner, the objective was to understand the impact that Hydrosome H2O could have on the yield of a target compound from a precision fermentation

Design

An engineered strain of E.coli, designed to produce a specific glycochemical, was grown in the presence of DI water and Hydrosome H2O (DI water with proprietary ultrafine bubbles). The fermentations were conducted in shaker flasks with all conditions identical except for the water used.

Results

There was a measurable increase in both the biomass (+20%) and titers (+15%) in the flasks containing Hydrosome H2O.

E. coli Growth (OD 600)

Production of Glycochemical

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