Objective
The objective of this study, done at the University of Illinois Integrated Bioprocessing and Research Laboratory (IBRL), was to demonstrate the impact of Hydrosome Labs technology on cell growth and biomass in a pilot scale fed batch fermentation.
Design
E.coli was grown in a 400L fed batch bioreactor. In the test leg, ultrafine bubbles were infused into the fermentation continuously using Hydrosome Labs technology. No bubbles were added for the control leg. All other conditions were identical.
Results
The test leg using Hydrosome Labs technology had a 2x higher final biomass and a 25% faster exponential onset time.
Doubling Time Enhancement
~2x Faster Doubling Time with Hydrosome Technology
Glucose Utilization (CFU/g of Glucose)
